| Titel: | Treating hypertension with a device that slows and regularises breathing: a randomised, double-blind controlled study |
|---|---|
| Autor: | Schein, MH Gavish, B Herz, M Rosner-Kahana, D Naveh, P Knishkowy, B Zlotnikov, E Ben-Zvi, N Melmed, RN |
| Mediengruppe: | journal article |
| Herausgeber: | --- |
| Zeitschrift: | Journal of Human Hypertension |
| Jahr: | 2001 |
| Band: | 15 |
| Heft: | 4 |
| Seiten: | 271-278 |
| Sprache: | englisch |
| Abstract: | Objective: To examine the efficacy of a new device, which slows and regularises breathing, as a non-pharmacological treatment of hypertension and thus to evaluate the contribution of breathing modulation in the blood pressure (BP) reduction. Design and setting: Randomised, double-blind controlled study, carried out: in three urban family practice clinics in Israel. Patients: Sixty-five male and female hypertensives, either receiving antihypertensive drug therapy or unmedicated. Four patients dropped out at the beginning of the study. Intervention: Self treatment at home, 10 minutes daily for 8 consecutive weeks, using either the device (n 32), which guides the user towards slow and regular breathing using musical sound patterns, or a Walkman, with which patients listened to quiet music (n = 29). Medication was unchanged 2 months prior to and during the study period. Main outcome measures: Systolic BP, diastolic BP and mean arterial pressure (MAP) changes from baseline. Results: BP reduction in the device group was significantly greater than a predetermined 'clinically meaningful threshold' of 10.0, 5.0 and 6.7 mm Hg for the systolic BP, diastolic BP and MAP respectively (P = 0.035, P = 0.0002 and P = 0.001). Treatment with the device reduced systolic BP, diastolic BP and MAP by 15.2, 10.0 and 11.7 mm Hg respectively, as compared to 11.3, 5.6 and 7.5 mm Hg (P = 0.14, P = 0.008, P = 0.03) with the Walkman. Six months after treatment had stopped, diastolic BP reduction in the device group remained greater than the 'threshold' (P < 0.02) and also greater than in the Walkman group (P = 0.001). Conclusions: The device was found to be efficacious in reducing high BP during 2 months of self-treatment by patients at home. Breathing pattern modification appears to be an important component in this reduction. |